Catalogue Number:B400180
Chemical Name:1,3-Bis(2-acetyl-3-hydroxyphenoxy)-2-hydroxypropane
Synonyms:USP Cromolyn Sodium Related Compound A; 1,3-Bis(2-acetyl-3-hydroxyphenoxy)-2-propanol; 2′,2”’-[(2-Hydroxytrimethylene)dioxy]bis[6′-hydroxyacetophenone;
CAS Number:16150-44-0
Molecular Formula:C₁₉H₂₀O₇
Appearance:Pale Yellow to Light Beige Solid
Melting Point:167-169°C
Molecular Weight:360.36
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly, Heated), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1,3-Bis(2-acetyl-3-hydroxyphenoxy)-2-hydroxypropane is an impurity in the synthesis of Sodium Cromoglycate (C815000), a chromone complex which blocks mast cell degranulation.
References:Ashton, M.J., et al.: Toxicol. Appl. Pharmacol., 26, 319 (1973), Friday, G.A., et al.: Am. J. Ophthalmol., 95, 169 (1983),
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