Catalogue Number:B399710
Chemical Name:BIRT 377
Synonyms:(5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-Imidazolidinedione;
CAS Number:213211-10-0
Molecular Formula:C₁₈H₁₅BrCl₂N₂O₂
Molecular Weight:442.13
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BIRT 377 inhibits lymphocyte function-associated antigen-1(LFA-1), which is a cell-adhesion molecule that mediates important immunological events (1). BIRT 377 is also a leukocyte adhesion suppressor (1). Studies showed that BIRT 377 inhibits lymphocyte activity both in vitro and in vivo (2)
References:(1) Aaron, J., et al.: Org. Biomol. Chem., 2015,13, 1463-1469
(2) Kelly, T. A., et al.: J Immunol. (1999) 163:5173-7.
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com
