Catalogue Number:B398960
Chemical Name:1,4’-Bipiperidine
Synonyms:4-(1-Piperidino)piperidine; 1-(4-Piperidyl)piperidine; 1-(Piperidin-4-yl)piperidine; 4-(1-Piperidinyl)piperidine; 4-Piperidinopiperidine; [1,4′]Bipiperidinyl
CAS Number:4897-50-1
Molecular Formula:C₁₀H₂₀N₂
Appearance:Off-White to Pale Red Solid
Melting Point:58-63°C
Molecular Weight:168.28
Storage:20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:1,4’-Bipiperidine is used in the synthesis of selective sphingosine kinase 1 inhibitors used as a therapeutic agent for proliferative diseases. Also used in the synthesis of calcitonin gene-related (CGRP) receptor antagonists.
References:Baek, D. et al.: Chem. Comm., 49, 2136 (2013); Han, X. et al.: Bioorg. Med. Chem. Lett., 23, 1870 (2013);
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