Catalogue Number:B382095
Chemical Name:Bictegravir
Synonyms:GS-9883; (2R,5S,13aR)-2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-2,5-Methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
CAS Number:1611493-60-7
Molecular Formula:C₂₁H₁₈F₃N₃O₅
Appearance:White to Off-White Solid
Melting Point:>130°C (dec.)
Molecular Weight:449.38
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:Bictegravir, is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
References:Tsiang M. et al.: Antimicrob Agents Chemother. 2016 Nov 21;60(12):7086-7097;
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