Catalogue Number:B372000
Chemical Name:BHPI
Synonyms:3,3-Bis(p-hydroxyphenyl)-7-methyl-2-Indolinone; 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one; 3,3-Bis-(4-hydroxyphenyl)-7-methyl-1,3-dihydro-2H-indol-2-one;
CAS Number:56632-39-4
Molecular Formula:C₂₁H₁₇NO₃
Molecular Weight:331.36
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial and ovarian cancer cell lines.
References:Andruska, N. et al.: PNAC. Sci. U.S.A., 112, 4737 (2015);
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