Catalogue Number:B327100
Chemical Name:Betamethasone 11,21-Diacetate
Synonyms:(11?,16?)-11,21-Bis(acetyloxy)-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione; Betamethasone Acetate EP Impurity C
Impurity:Betamethasone Acetate EP Impurity C
CAS Number:330157-05-6
Molecular Formula:C₂₆H₃₃FO₇
Appearance:Pale Brown to Light Brown Solid
Melting Point:>214C (dec.)
Molecular Weight:476.53
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betamethasone 11?,21-Diacetate is an impurity of Betamethasone 21-Acetate (B327025); a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.
References:Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003); Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007)
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