Catalogue Number:B327030
Chemical Name:Betamethasone 21-Phosphate Disodium Salt
Synonyms:(11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione Sodium Salt; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene
Impurity:Dexamethasone Sodium Phosphate EP Impurity B
CAS Number:151-73-5
Alternate CAS #
360-63-4
Molecular Formula:C₂₂H₂₈FNa₂O₈P
Appearance:White to Off-White Solid
Melting Point:206-211°C
Molecular Weight:516.4
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Sparingly)
Stability
Hygroscopic
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betamethasone 21-Phosphate Disodium Salt (Dexamethasone Sodium Phosphate EP Impurity B) is a Betamethasone derivative. It is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.
References:Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),
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