Catalogue Number:B315190
Chemical Name:N-Benzyl-p-Toluenesulfonamide
Synonyms:4-Methyl-N-(phenylmethyl)benzenesulfonamide; Benzyl(4-toluenesulfonyl)amine; N-Benzyl-p-tosylamide; N-Tosylbenzylamine; NSC 37123; BTS
CAS Number:1576-37-0
Molecular Formula:C₁₄H₁₅NO₂S
Appearance:White to Off-White Solid
Melting Point:114-116°C
Molecular Weight:261.34
Storage:-20°C
Solubility:Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin’s interaction with F-actin. Does not affect platelet myosin II.
References:Cheung, A., et al.: Nat. Cell Biol., 4, 83 (2002), Dentel, J.N., et al.: Am. J. Physiol. Cell Physiol., 288, C824 (2005)
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