Catalogue Number:B288835
Chemical Name:2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-1H-inden-1-one
Synonyms:5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-Inden-1-one
CAS Number:2230493-73-7
Alternate CAS #
120014-06-4
Molecular Formula:C₂₄H₂₇NO₃
Molecular Weight:377.48
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-1H-inden-1-one is an impurity of Donepezil (CAT# D531750), which is a a potent acetylcholinesterase inhibitor and cognitive enhancer clinically used to treat neurodegenerative diseases. It can be useful in the green preparation of aldehydes/ketones and amides.
References:Giacomini, A. C. V. V., et al.: J. Psychopharmacol. (London, U. K.), 34, 1449 (2020) ; Zhang, Y., et al.: Nat. Protoc., 15, 822 (2020)
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