Catalogue Number:B208555
Chemical Name:(2R,3S)-N-Benzoyl-3-phenyl Isoserine Ethyl Ester
Synonyms:(αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid Ethyl Ester;
CAS Number:153433-80-8
Molecular Formula:C₁₈H₁₉NO₄
Appearance:White to Off-White Solid
Melting Point:165-168°C
Molecular Weight:313.35
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Amino Acids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2R,3S)-N-Benzoyl-3-phenylisoserine ethyl ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine ethyl ester shows cytotoxic, antiviral and immunomodulatory activity.
References:Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);
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