Catalogue Number:B206635
Chemical Name:(αR,2R)-2-(2-Benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-1-azetidineacetic Acid Diphenylmethyl Ester
CAS Number:87579-79-1
Molecular Formula:C₂₈H₂₄N₂O₃S₃
Molecular Weight:532.7
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(αR,2R)-2-(2-Benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-1-azetidineacetic Acid Diphenylmethyl Ester is used in the synthesis of 4-Sulfonylazetidin-2-ones which exhibits anti-cancer effects;Also, it is an intermediate used in the synthesis of Tazobactam Sodium Salt-15N3 (T010103), which is a labeled analogue of Tazobactam Sodium Salt (T010100), which is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.
References:Veinberg, G., et al.: Chem. Heterocycl. Compd., 40, 816-822 (2004); Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991), Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000), Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001)
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