Catalogue Number:B203635
Chemical Name:2(3H)-Benzofuranone
Synonyms:2,3-Dihydrobenzofuran-2-one; 2-Benzofuranone; 2-Coumaranone; 2-Coumarone; 3H-Benzofuran-2-one; Benzo[b]furan-2(3H)-one; Cumaranone; Isophthalide; NSC 227414; o-Hydroxyphenylacetic acid γ-lactone; α-Coumaranone
CAS Number:553-86-6
Molecular Formula:C₈H₆O₂
Appearance:Yellow Solid
Melting Point:48-50°C
Molecular Weight:134.13
Storage:4°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:2(3H)-Benzofuranone is used in the synthesis of indolinones and analogues in the treatment of cancers. Also used in the synthesis of antitumor bis-indole derivatives. Impurity in the synthesis of Azoxystrobin (A965150).
References:Andreani, A. et al.: J. Med. Chem., 55, 2078 (2012); Andreani, A. et al.: Bioorg. Med. Chem., 18, 3004 (2010);
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