CAS:45170-31-8|N-Boc-N-methyl-L-valine

Catalogue Number:B201920
Chemical Name:N-Boc-N-methyl-L-valine
Synonyms:N-[(1,1-Dimethylethoxy)carbonyl]-N-methyl-L-valine; (2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic Acid;
CAS Number:45170-31-8
Molecular Formula:C₁₁H₂₁NO₄
Appearance:Off-White Solid
Melting Point:52-56°C
Molecular Weight:231.29
Storage:-20°C
Solubility:Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Building Blocks; Chiral Molecules; Amino Acids;
Applications:N-Boc-N-methyl-L-valine is an amino acid derived compound that functions as a useful pharmaceutical intermediate and also employed as a reagent used in organic synthesis. It is used in the synthesis of lactam analog of actinomycin D, a potential antitumor chemotherapeutic agent.
References:Moore, S., et al.: J. Med. Chem., 19, 766 (1976); Colombo, R., et al.: J. Org. Chem., 81, 10302 (2016); Nicolaou, K. C., et al.: J. Am. Chem. Soc., 138, 1698 (2016); Hattori, K., et al.: Org. Biomol. Chem., 14, 2090 (2016)
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