CAS:79473-21-5|N-[N-Boc-D-alaninyl]-D-alanine

Catalogue Number:B201170
Chemical Name:N-[N-Boc-D-alaninyl]-D-alanine
Synonyms:N-[(1,1-Dimethylethoxy)carbonyl]-D-alanyl-D-alanine
CAS Number:79473-21-5
Molecular Formula:C₁₁H₂₀N₂O₅
Molecular Weight:260.29
Category:Research Tools; Chiral Molecules; Molecular Biology; Amino Acids/Peptides;
Applications:N-[N-Boc-D-alaninyl]-D-alanine is an intermediate in the synthesis of N-​Acetyl-​D-​alanyl-D-alanine (A168068), which was used as the target in the target-accelerated combinatorial synthesis of vancomycin dimers. D-Ala-D-Ala possess the greatest affinity for vancomycin. Vancomycin and N-​Acetyl-​D-​alanyl-D-alanine are used as a model system to demonstrate the use of affinity capillary eletrophoresis.
References:Nicolaou, K., et al.: Angew. Chem. Int. Ed., 39, 3823 (2000); Chu, Y., et al.: J. Org. Chem., 57, 3524 (1992);
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