CAS:189035-19-6|11-(1,3-Benzodioxol-5-yl)-5,17-dihydroxy-17-(1-propynyl)-estr-9-en-3-one Cyclic 1,2-Ethanediyl Acetal

Catalogue Number:B198855
Chemical Name:11-(1,3-Benzodioxol-5-yl)-5,17-dihydroxy-17-(1-propynyl)-estr-9-en-3-one Cyclic 1,2-Ethanediyl Acetal
CAS Number:189035-19-6
Molecular Formula:C₃₀H₃₆O₆
Molecular Weight:492.6
Category:Standards; Steroids;
Applications:11-(1,3-Benzodioxol-5-yl)-5,17-dihydroxy-17-(1-propynyl)-estr-9-en-3-one Cyclic 1,2-Ethanediyl Acetal is an intermediate used in the synthesis of (11β,17β)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one (B198850), which is a glucocorticoid receptor (GR) antagonists.
References:Verdouw, P. M., et al.: Pharmacol. Biochem. Behav., 154, 11-19 (2017); Reynolds, A. R., et al.: Drug Alcohol. Dep., 154, 100-104 (2015)
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