Catalogue Number:B196952
Chemical Name:1-Benzhydrylpiperazine-d8
Synonyms:1-(Diphenylmethyl)piperazine-d8; 4-(Diphenylmethyl)piperazine-d8; 4-Benzhydrylpiperazine-d8; Benzhydrylpiperazine-d8; N-(Diphenylmethyl)piperazine-d8; N-Benzhydrylpiperazine-d8; NSC 35536-d8; Norcyclizine-d8;
CAS Number:1330188-81-2
Alternate CAS #
841-77-0-unlabelled
Molecular Formula:C₁₇H₁₂D₈N₂
Appearance:Off-White to Yellow Solid
Melting Point:85 – 87°C
Molecular Weight:260.4
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-Benzhydrylpiperazine-d8 is a isotopically labelled Cinnarizine (C465300) impurity which is a calcium channel blocker with antiallergic and anti-vasoconstricting activity. Antihistaminic.
References:Zhang, H., et al.: Biochemistry, 43, 8290 (2004), Pandey, A., et al.: J. Pharm. Biomed. Anal., 20, 203 (1999), Andrews, S., et al.: J. Med. Chem., 53, 916 (2010); Barber, J.H., et al.: Pharmatherapeutica, 2, 401 (1980), Spedding, M., et al.: Arch. Pharmacol., 318, 234 (1982), Morad, et al.: Pharmacol. Res., 35, 177 (1997)
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