Chemical Name:S-Cinaclet
Synonyms:(S)-N-((R)-1-(Naphthalen-1-yl)ethyl)-2-(3-(trifluoromethyl)phenyl)propan-1-amine; (αR)-α-Methyl-N-[(2S)-2-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
CAS Number:2059891-96-0
Molecular Formula:C₂₂H₂₂F₃N
Molecular Weight:357.41
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:S-Cinaclet is an isomer of Cinacalcet (C441790), the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease.
References:Block, G, et al.: Am. J. Kidney Dis., 35, 1226 (2000), Moe, S., et al.: Am. J. Nephrol., 23, 369 (2003), Block, G., et al.: J. Am. Soc. Nephrol., 15, 2208 (2004).
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