Catalogue Number:A548495
Chemical Name:Allotetrahydrocorticosterone
Synonyms:(3α,5α,11β)-3,11,21-Trihydroxypregnan-20-one; 3α,11β,21-Trihydroxy-5α-pregnan-20-one; 3α,5α-Tetrahydrocorticosterone; 5α-Pregnane-3α,11β,21-triol-20-one; 5α-THB; 5α-Tetrahydrocorticosterone; 3α,11β,21-Trihydroxy-5α-pregnan-20-one;
CAS Number:600-63-5
Molecular Formula:C₂₁H₃₄O₄
Appearance:White to Off-White Solid
Melting Point:>180ºC (dec.)
Molecular Weight:350.49
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Stable under recommended storage conditions., Stable Under Recommended Storage C
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:Allotetrahydrocorticosterone displays the profile of a safe topical anti-inflammatory compound. Also, it strongly inhibits 11b-HSD2 and 11b-HSD1 dehydrogenase activity.
References:Gastaldello, A., et al.: Biochem. Pharmacol., 129, 73-84 (2017); Morris, D. J., et al.: Steroids, 79, 44-48 (2014)
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