Catalogue Number:A115635
Chemical Name:Acelarin
Synonyms:N-(2′-Deoxy-2′,2′-difluoro-P-phenyl-5′-cytidylyl)-L-alanine phenylmethyl Ester; NUC 1031
CAS Number:840506-29-8
Molecular Formula:C₂₅H₂₇F₂N₄O₈P
Molecular Weight:580.47
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Acelarin is a phosphoramidate transformation of the pancreatic and ovarian cancer chemotherapy Gemcitabine; and the first anti-cancer ProTide to enter the clinic.
References:Sarr, A., et al.: Sci. Rep., 9, 1 (2019); Blagden, S. P., et al.: Br. J. Cancer, 119, 815 (2018)
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