Catalogue Number:D289155
Chemical Name:11-Desethyl Irinotecan
Synonyms:(4S)-4-Ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl Ester [1,4′-Bipiperidine]-1′-carboxylic Acid; 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline, [1,4′-Bipiperidine]-1′-carboxylic Acid deriv.; 10-[4-(1-Piperidino)-1-piperidinocarbonyloxy]camptothecin;
CAS Number:103816-16-6
Molecular Formula:C₃₁H₃₄N₄O₆
Appearance:Yellow to Dark Yellow Solid
Melting Point:>170°C (dec.)
Molecular Weight:558.62
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:11-Desethyl Irinotecan is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500).
References:Yu,P., et al.: Biol. Pharma. Bull., 35, 1295 (2012); Wang, Y.Q., et al.: Bioorg. Med. Chem., 13, 5592 (2005);
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