Catalogue Number:D288731
Chemical Name:Desethyl Amiodarone Hydrochloride
Synonyms:2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochloride; Amiodarone EP Impurity B ; Amiodarone USP Related Compound B
Impurity:Amiodarone EP Impurity B / Amiodarone USP Related Compound B
CAS Number:96027-74-6
Alternate CAS #
freebase: 83409-32-9
Molecular Formula:C₂₃H₂₅I₂NO₃ • HCl
Appearance:White to Light Brown Solid
Melting Point:167-1700C (dec.)
Molecular Weight:617.26 + (36.46)
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Desethyl Amiodarone Hydrochloride (Amiodarone EP Impurity B) is a metabolite of Amiodarone, a non-selective ion channel blocker.
References:Ha, H., et al.: Eur. J. Clin. Pharmacol., 55, 807 (2000), Arai, K., et al.: J. Biochem., 132, 529 (2002), Carson, B., et al.: J. Med. Chem., 31, 623 (2002),
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