Catalogue Number:D232980
Chemical Name:(2’S)-2’-Deoxy-2’-fluoro-5-ethynyluridine
Synonyms:F-ara-EdU;
CAS Number:95740-26-4
Molecular Formula:C₁₁H₁₁FN₂O₅
Molecular Weight:270.21
Category:Standards; Carbohydrates and Oligosaccharides;
Applications:(2′S)-2′-Deoxy-2′-fluoro-5-ethynyluridine is a commonly used probe for DNA synthesis in vivo as it exhibits minimal impact on genome function in diverse tissue types. (2′S)-2′-deoxy-2′-fluoro-5-ethynyluridine is also ideally suited for metabolic DNA labeling when prolonged cell survival and undisturbed cell cycle progression are necessary, such as for pulse-chase experiments aimed at “birth dating” DNA in vivo.
References:Neef, A.B., et al.: P. Natl. Acad. Sci.., 108, 20404 (2011);
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