3-[4-(Aminomethyl)benzyloxy] Thalidomide

Chemical Name:3-[4-(Aminomethyl)benzyloxy] Thalidomide
Molecular Formula:C₂₁H₁₉N₃O₅
Molecular Weight:393.39
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-[4-(Aminomethyl)benzyloxy] Thalidomide is a derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
References:D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)
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