CAS:1187966-94-4|6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine

Catalogue Number:C989580
Chemical Name:6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine
CAS Number:1187966-94-4
Molecular Formula:C₂₀H₁₆FN
Appearance:White to Off-White Solid
Melting Point:121-123°C
Molecular Weight:289.35
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly, Heated)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is an impurity of Pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic.
References:Grobelny, P., et. al.: J. Pharmaceut. Biomed. Anal., 50, 597 (2009); Aoki, T., et al.: Arzneim.-Forsch., 47, 904 (1997); Yamada, I., et al.: Xenobiotica, 33, 789 (2003); Park, S., et al.: Clin. Ther., 27, 1074 (2005)
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