CAS:1187966-93-3|(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid

Catalogue Number:C989575
Chemical Name:(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid
Synonyms:(βR,δS)-6-Cyclopropyl-10-fluoro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid
CAS Number:1187966-93-3
Molecular Formula:C₂₅H₂₂FNO₄
Appearance:Pale Beige to Light Beige Solid
Molecular Weight:419.44
Storage:-20°C, Hygroscopic
Solubility:Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is an impurity of pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic.
References:Grobelny, P., et. al.: J. Pharmaceut. Biomed. Anal., 50, 597 (2009); Aoki, T., et al.: Arzneim.-Forsch., 47, 904 (1997); Yamada, I., et al.: Xenobiotica, 33, 789 (2003); Park, S., et al.: Clin. Ther., 27, 1074 (2005)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com