Catalogue Number:C988970
Chemical Name:Cycotiamine
Synonyms:N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[1-(2-oxo-1,3-oxathian-4-ylidene)ethyl]formamide; CCT; Carbothiamine; Cometamine; Commetamin; Cyclocarbothiamine; Cyclothiamine; Cyclotiamine; Cycothiamine; Thiocarbonic Acid Cyclic O,S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide;
CAS Number:6092-18-8
Molecular Formula:C₁₃H₁₆N₄O₃S
Appearance:White to Light Yellow Solid
Melting Point:>168°C (dec.)
Molecular Weight:308.36
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Thiamine (T344185) derivative used in the treatment of neurogenic bladder dysfunction. It is absorbed from the intestine and rapidly metabolized into thiamine in the blood. Studies suggest that it has stimulant action on intestinal motility.
References:Nihira, H. et al.: Hinyok. Kiyo, 12, 823 (1966); Shiobara, Y. et al.: Bitamin, 37, 306 (1968); Kuriaki, K. et al.: Bitamin, 41, 30 (1970);
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