Catalogue Number:C605575
Chemical Name:7-Chloro-3-methyl-4H-1,2,4-benzothiadiazine 1-Oxide
CAS Number:31365-76-1
Molecular Formula:C₈H₇ClN₂OS
Molecular Weight:214.67
Category:Building Blocks; Miscellaneous;
Applications:7-Chloro-3-methyl-4H-1,2,4-benzothiadiazine 1-Oxide is an intermediate in the synthesis of 1-Amino-7-chloro-3-methylbenzo[e][1,2,4]thiadiazine 1-oxide (A605595, a derivative of 3-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide (M292970) which functions in structure activity relations analysis of benzothiadiazine compounds as hyperglycemic agents by correlating with the reduction in urine output in vivo and insulin production both in vivo and in vitro, and also functions as an antihypertensive agent.
References:Wales, J. K., et al.: J. Pharm. Exp. Ther., 164, 421 (1968); Topliss, J. G., et al.: J Med. Chem., 7, 269 (1964)
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