5α-Cholestan-3α,7α,12α-triol

Chemical Name:5α-Cholestan-3α,7α,12α-triol
Synonyms:(3R,5R,7R,10R,12S,13R,17R)-5,10,13-Trimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol
CAS Number:16669-19-5
Molecular Formula:C₂₈H₅₀O₃
Molecular Weight:434.69
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:5α-Cholestan-3α,7α,12α-triol is a synthetic bile acid acting as an agonist for the TGR5 G protein-coupled receptor that is activated by bile acids. Potential use in treatment towards obesity related disorders.
References:Ali, S. et al.: J. Lipid. Res., 17, 386 (1976); Iguchi, Y. et al.: J. Lipid Res., 51, 1432 (2010);
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